Hydrogen sulfide for organ protection

MAVS Mediates Protection against Myocardial Ischemic Injury with Hydrogen Sulfide

Background: Hydrogen sulfide (H 2 S) has been shown to protect against myocardial ischemic and inflammatory injury in part by preserving mitochondrial integrity. Since mitochondrial antiviral signaling (MAVS) protein has been implicated in attenuating Bax-mediated cytochrome c release from mitochondria caused by oxidative stress or ischemia, we sought to determine whether MAVS mediates the card...

Biology for Physiological Hydrogen Sulfide

Discrepant Tests for Hydrogen Sulfide.

Kligler and Triple Sugar Iron (TSI) media have been considered to be interchangeable for the purpose of detecting hydrogen sulfide production in the family Enterobacteriaceae. Contrary evidence is presented in this report. From various sources, 11 cultures were isolated which yielded a positive hydrogen sulfide reaction on Kligler medium and a negative reaction on TSI. Biochemically, these cult...

Electrochemical hydrogen sulfide biosensors.

The measurement of sulfide, especially hydrogen sulfide, has held the attention of the analytical community due to its unique physiological and pathophysiological roles in biological systems. Electrochemical detection offers a rapid, highly sensitive, affordable, simple, and real-time technique to measure hydrogen sulfide concentration, which has been a well-documented and reliable method. This...

Bronchodilatory Effect of Hydrogen Sulfide in Rat

Objective(s) The aims of present study were to elucidate the effect of NaHS as a H2S donor on precontracted rat trachea smooth muscle, role of epithelium and nitric oxide in this action. Materials and Methods Tracheal rings from male adult Wistar rats were isolated and mounted in an organ bath containing Krebs–Henseleit solution under 1.5 g resting tension and contractions were recorded isom...